Tibofem (Tibolone 2.5mg Tablets)

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Tibofem (Tibolone 2.5mg Tablets) used for?

Tibofem (Tibolone 2.5mg Tablets) are a hormone replacement therapy (HRT) used to help relieve symptoms of menopause, caused by reduced production of oestrogen after menopause or following surgical removal of the ovaries. These symptoms include, hot flushes, night sweats, sleeplessness, vaginal dryness, headaches, mood swings, lack of concentration and loss of energy. Tibofem (Tibolone 2.5mg Tablets) are also used to help prevent postmenopausal bone loss (osteoporosis) and reduce risk of fracture. Tibofem (Tibolone 2.5mg Tablets) are intended only for post-menopausal women who are over 60 years and who cannot take other HRT medication for the treatment of oestrogen deficiency or other medication for prevention of bone mineral density loss.


Tibofem (Tibolone 2.5mg Tablets) work?

Tibofem (Tibolone 2.5mg Tablets) contain tibolone, a synthetic steroid hormone that is broken down by the body’s metabolism into three compounds that act in a similar way to naturally produced oestrogen, progesterone and testosterone. These metabolites are also tissue-specific which means that they only act on certain tissues. Tibofem (Tibolone 2.5mg Tablets), once metabolised, have oestrogenic effects on bone, vaginal and breast tissue, whereas it has progestogen activity on the endometrium (lining of the uterus) and androgenic effects (like testosterone) in the brain and liver; these actions help restore the hormonal balance to relieve menopausal symptoms like vaginal atrophy, loss of bone density and osteoporosis, as well as other symptoms, such as reducing hot flushes and improved libido. Tibofem (Tibolone 2.5mg Tablets) also have other beneficial effects like lowering cholesterol levels, which tend to increase after menopause.


Side Effects of Tibofem (Tibolone 2.5mg Tablets)?

The most commonly reported side effects when taking Tibofem (Tibolone 2.5mg Tablets) include: lower abdominal pain, abnormal hair growth, vaginal, discharge bleeding or spotting, breast tenderness, haemorrhage, genital itching, vaginal candidiasis (yeast infection), thickened endometrial (lining of the uterus) wall, abnormal growth of the cervix, inflammation of the vagina and vulva (vulvovaginitis).


Tibofem (Tibolone 2.5mg Tablets) contain?

Tibofem (Tibolone 2.5mg Tablets) contain the active ingredient tibolone 2.5 mg, a synthetic steroid hormone that is used for hormone replacement therapy (HRT).


When should Tibofem (Tibolone 2.5mg Tablets) not be used?

You should not use Tibofem (Tibolone 2.5mg Tablets) if you:

  • are allergic to tibolone or any ingredients in Tibofem (Tibolone 2.5mg Tablets)
  • are pregnant or are breastfeeding
  • have a past or family history of carcinoma of the breast, endometrial carcinoma or liver disease
  • have a history of thrombosis (blood clots) in the legs( thromboembolism) or lung (pulmonary embolism)
  • have a history of heart disease, stroke, severe uncontrolled high blood pressure
  • have abnormal vaginal bleeding of unknown cause
  • have liver disease or the blood disorder porphyria
  • are taking medicines that interact with Tibofem (Tibolone 2.5mg Tablets) including: anticoagulant like warfarin, anticonvulsants like phenytoin and carbamazepin, anti-infectives like rifampicin, rifabutin, the sedative midazolam
  • Availability: 1000
  • Model: Tibofem
  • Manufacturer: Cipla

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