Heart Health

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Atorlip (Atorvastatin 10mg Tablets) (PVJ093)
Atorlip (Atorvastatin 10mg Tablets) is used to lower high levels of cholesterol and other fats (triglycerides) in the blood and reduce risk of heart disease that can be caused by high cholesterol. Atorlip (Atorvastatin 10mg Tablets) lowers levels of total cholesterol as well as reducing “bad” cholesterol (LDL) that can cause arteries to become hardened and blocked, and also increases levels of “good” cholesterol (HDL) that helps unblock hardened arteries. Atorlip (Atorvastatin 10mg Tablets) is used, in conjunction with a low-fat diet, to treat patients at risk of coronary heart disease (CHD) or patients with high cholesterol (hypercholesterolaemia), inherited or due to lifestyle (high-fat diet, obesity and lack of exercise), who have not responded to a low-fat diet and lifestyle changes alone.
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Carloc (Carvedilol 12.5mg Tablets) (PVJ0343)
Carloc (Carvedilol 12.5mg Tablets) (also known as Coreg in the US) contain carvedilol, which is a non-selective beta-blocker and acts as a beta1 and beta2 receptor antagonist, with some action as an alpha-receptor antagogist. Carvedilol in Carloc (Carvedilol 12.5mg Tablets) works by blocking the action of chemicals called catecholamines, such as adrenaline and noradrenaline (epinephrine and nor epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works by stimulating beta-receptors in the heart, which increases heart rate and causes constriction (narrowing) of blood vessels. Carvedilol in Carloc (Carvedilol 12.5mg Tablets) blocks the beta-receptors in the heart, to slow heart rate and reduce the force needed to pump blood around the body, which means that the heart needs less oxygen. This action relieves the pain of angina which is caused by increased workload and lack of oxygen to the heart on exertion. Carvedilol in Carloc (Carvedilol 12.5mg Tablets) also blocks alpha-receptors found in peripheral blood vessel walls, and this causes them to relax and widen (vasodilation), reducing the resistance to blood flow. The combined action of alpha and beta blockade by Carloc (Carvedilol 12.5mg Tablets) reduces the force needed by the heart to pump blood and increases blood flow and oxygen to the heart, while at the same time reducing resistance to blood circulating in peripheral vessels by causing vasodilation, which helps lower blood pressure; as well as helping the heart pump more efficiently, thereby reducing feelings of breathlessness on exertion due to weakened heart muscles as in congestive heart failure.
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